45 Schofield is similar to the 45 Colt. Differences include head diameter approximately .010" larger, case length is 1.090" to 1.100" compared to 1.273" to 1.283" in the 45 Colt. Substantially less internal capacity for shooting light loads in most 45 Colt guns with no modifications. You may need to tune extractor on some lever action rifles, or decrease diameter of the ratchet on the cylinder by .010 to accommodate the larger head diameter in Ruger Vaquero and Colts. Also increases magazine capacity in rifles.